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Compounds

Cat No. Product Name Synonyms Targets
T28368 PF-04859989 HCl PF 04859989,PF04859989,PF-04859989HCl,PF-04859989 Others
PF-04859989 HCl is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid. PF-04859989 HCl has been implicated in s...
T24617 PF-04859989
PF-04859989 is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II. PF-04859989 is ~1000-fold selective for KAT II over human KAT I, KAT III, and KAT IV. PF-04859989 has IC50 values of 23 nM for ...
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